Author’s response to reviews Title: Increased circulating bioactive C-type natriuretic peptide is associated with reduced heart rate variability in patients with chronic kidney disease Authors:

Increased circulating bioactive C-type natriuretic peptide is associated with reduced heart rate variability in patients with chronic kidney disease

BACKGROUND C-type natriuretic peptide (CNP) is a member of the natriuretic peptide family and have been implicated to be involved in maintaining vascular homeostasis and acting as a cardiac chronotropic agent in experimental studies. However, clinical evidence of its participation in cardiovascular regulation is lacking, especially in patients with chronic kidney disease (CKD). We aimed to expl...

Clinical and Biochemical Assessments of Circulating B-Type Natriuretic Peptide as a Useful Marker in Pediatric Cardiac Patients

Background Although the left ventricle is the major site of BNP secretion in response to cardiac pressure or volume overload, the myocytes of both atria and ventricles secrete B- type natriuretic peptide (BNP). This study aimed to assess and compare the plasma levels of BNP in common pediatric cardiac diseases to clarify its pathophysiological role and evaluate its po...

Author's response to reviews Title: B-Type Natriuretic Peptide versus Amino Terminal Pro-B Type Natriuretic Peptide: Selecting the optimal heart failure marker in patients with impaired kidney function. Authors:

Author’s response to reviews Title: Red Cell Distribution Width Associated with Adverse Cardiovascular Outcomes in Patients with Chronic Kidney Disease Authors:

Title: Red Cell Distribution Width Associated with Adverse Cardiovascular Outcomes in Patients with Chronic Kidney Disease Authors: Yueh An Lu ([email protected]) Pei Chun Fan ([email protected]) Cheng Chia Lee ([email protected]) Victor Chien-Chia Wu ([email protected]) Ya Chung Tian ([email protected]) Chih Wei Yang ([email protected]) Yung Chang Chen ([email protected]) Chih...

Evaluation of Brain Natriuretic Peptide, Tumor Necrosis Factor and Interleukin-6 Plasma Levels in Infants and Children with Congenital Heart Disease

Background Congenital heart disease (CHD) is the most common cause of major congenital birth defect. The aim of this study was to investigate the association of CHD with serum levels of Tumor necrosis factor-α (TNFα), Interleukin 6 (IL-6), and B-type Natriuretic Peptide (BNP) in infant and children. Materials and Methods The present study was conducted in Heshmat heart hospital and 17 Shahrivar...